1. Liang Y, Ormazabal-Toledo R, Yao S, Shi YS, Herrera-Molina R, Montag D, Lin X. (2024) Deafness causing neuroplastin missense variants fail to promote plasma membrane Ca2+-ATPase levels and Ca2+ transient regulation in brain neurons. J Biol Chem. doi: 10.1016/j.jbc.2024.107474.
2. Adasme T, Hidalgo C, Herrera-Molina R (2023) Editorial: Emerging Views and Players in Neuronal Calcium Signaling: Synaptic Plasticity, Learning/Memory, Ageing and Neuroinflammation. Frontiers in Cellular Neuroscience. doi: 10.3389/fncel.2023.1197417
3. Malci A, Lin X, Shi YS, Herrera-Molina R (2023) Neuroplastin in Ca2+ signal regulation of plasticity in glutamatergic synapses. Neural Regeneration Research 18(8):1705-1706
4. Malci A, Lin X, Sandoval R, Gundelfinger ED, Naumann M, Seidenbecher CI, Herrera-Molina R (2022) Ca2+ signalling in postsynaptic neurons: neuroplastin-65 regulates the interplay between plasma membrane Ca2+-ATPases and ionotropic glutamate receptors. Cell Calcium.106:102623. doi: 10.1016/j.ceca.2022.102623
5. Guzmán Salas S, Weber A, Malci A, Lin X, Herrera-Molina R, Cerpa W, Dorador C, Signorelli J, Zamorano P (2022) The metabolite p-cresol impairs dendritic development, synaptogenesis and synapse function in hippocampal neurons: Implications to autism spectrum disorder. J Neurochem. 161(4):335-349. doi: 10.1111/jnc.15604
6. Lin X, Brunk MGK, Yuanxiang P, Curran AW, Stöber F, Goldschmidt J, Gundelfinger ED, Vollmer M, Happel MFK, Herrera-Molina R, Montag D (2021) Neuroplastin expression is essential for hearing and hair cell PMCA expression. Brain Structure and Functio doi: 10.1007/s00429-021-02269-w
7. Lin X, Liang Y, Herrera-Molina R, Montag D (2021) Neuroplastin in Neuropsychiatric Diseases. Genes 12(10):1507. doi: 10.3390/genes12101507
8. Ilic K, Lin X, Malci A, Stojanović M, Puljko B, Rožma M, Vukelić Z, Heffer M, Montag D, Schnaar RL, Kalanj-Bognar S, Herrera-Molina R, Mlinac-Jerkovic K (2021) Plasma membrane calcium ATPase-Neuroplastin complexes are selectively stabilized in GM1-containing lipid rafts. J. Mol. Sci. 22(24):13590. doi: 10.3390/ijms222413590
9. Vemula SK, Malci A, Junge L, LehmannAC, RamaR, HradskyJ, Matute RA, Weber A, Naumann M, Kreutz MR, Seidenbecher CI, Gundelfinger ED, Herrera-Molina R (2020) The interaction of TRAF6 with neuroplastin promotes spinogenesis during early neuronal development. Cell Dev. Biol. doi: 10.3389/fcell. 2020.57951
10. García F, Lobos P, Ponce A, Cataldo K, Meza D, Farías P, Estay C, Oyarzun-Ampuero F, Herrera-Molina R, Paula-Lima A, Ardiles ÁO, Hidalgo C, Adasme T, Muñoz P (2020) Astaxanthin Counteracts Excitotoxicity and Reduces the Ensuing Increases in Calcium Levels and Mitochondrial Reactive Oxygen Species Generation. Mar Drugs 18(6):335
11. Luarte A, Henzi R, Fernández A, Gaete D, Cisternas P, Pizarro M, Batiz LF, Villalobos I, Masalleras M, Vergara R, Varas-Godoy M, Abarzua-Catalan L, Herrera-Molina R, Lafourcade C, Wyneken U (2020) Astrocyte-Derived Small Extracellular Vesicles Regulate Dendritic Complexity through miR-26a-5p Activity. Cells 10;9(4):930
12. Ilic K, Auer B, Mlinac-Jerkovic K, Herrera-Molina R (2019) Neuronal signalling by Thy-1 in nanodomains with specific ganglioside composition: Shall we open the door to a new complexity?. Cell Dev. Biol. doi: 10.3389/fcell.2019.00027.
13. Xia Z, Arias-Gil G, Deckert M, Vollmer M, Curran A, Herrera-Molina R, Brosch M, Krug K, Schmidt B, Ohl FW, Lippert MT, Takagaki K (2019) Electrochemical Roughening and Carbon Nanotube Coating of Tetrodes for Chronic Single-Unit Recording. bioRxiv: 738245.
14. Bruna B, Lobos P, Herrera-Molina R, Hidalgo C, Paula-Lima A, Adasme T (2018) The Signaling Pathways Underlying BDNF-Induced Nrf2 Hippocampal Nuclear Translocation Involve ROS, RyR-Mediated Ca2+ Signals, ERK and PI3K. BBRC 20;505(1):201-207
15. Lang D, Schott BH, van Ham M, Morton L, Parlog A, Kulikovskaja L, Herrera-Molina R, Pielot R, Montag D, Jaensch L, Gundelfinger ED, Smalla KH, Dunay IR (2018) Chronic Toxoplasma-induced neuroinflammation is associated with distinct changes in the synaptic protein composition. J Neuroinflammation 15(1):216. doi: 10.1186/s12974-018-1242-1
16. Lagos-Cabré R, Brenet M, Díaz J , Pérez RD, Pérey LA, Herrera-Molina R, Quest AFG, Leyton L (2018) Intracellular Ca2+ increases and Connexin 43 hemichannel opening are necessary but not sufficient for Thy-1-induced astrocyte migration. Int J Mol Sci 19(8) doi: 10.3390/ijms19082179
17. Herrera-Molina R, Mlinac-Jerkovic K, Ilic K, Stöber F, Kumar Vemula S, Sandoval M, Jovanov Milosevic N, Simic G, Smalla KH, Goldschmidt J, Kalanj Bognar S, Montag D (2017) Neuroplastin deletion in glutamatergic neurons impairs selective brain functions and calcium regulation: implication for cognitive deterioration. Scientific Report 4;7(1):7273
18. Bhattacharya S*, Herrera-Molina R*, Sabanov V, Ahmed T, Iscru E, Stöber F, Richter K, Fischer KD, Angenstein F, Goldschmidt J, Beesley PW, Balschun D, Smalla KH, Gundelfinger ED, Montag D (2017) Genetically-induced retrograde amnesia of associative memories after neuroplastin ablation. Biological Psychiatry 81:124-135 (*co-first authorship)
19. Lagos-Cabré R, Alvarez A, Kong M, Burgos-Bravo F, Cárdenas A, Rojas-Mancilla E, Pérez-Nuñez R, Herrera-Molina R, Rojas F, Schneider P, Herrera-Marschitz M, Quest AFG, van Zundert B, Leyton L (2017) αVβ3 Integrin regulates astrocyte reactivity. J Neuroinflammation 29;14(1):194
20. Korthals M, Langnaese K, Smalla KH, Kähne T, Herrera-Molina R, Handschuh J, Lehmann AC, Herbert I, Mamula D, Naumann M, Seidenbecher CI, Tedford K,. Gundelfinger ED, Montag D, Fischer KD, Thomas U (2017) A complex of Neuroplastin and Plasma Membrane Calcium ATPase controls T cell activation. Scientific Report 21;7(1):8358
21. Maldonado H, Calderon C, Kobler O, Zuschratter W, Ramirez O, Härtel S, Schneider P, Quest AFG, Herrera-Molina R*, Leyton L* (2016) Integrin-induced changes in the Thy-1/CBP/Csk complex regulate the Src/RhoA/ROCK axis to alter the neuronal cytoskeleton. BBA-Mol Cell Research 1864(2):243-254 (*co-corresponding authorship)
22. Herrera-Molina R, Sarto-Jackson I, Montenegro-Venegas C, Heine M, Smalla KH, Seidenbecher CI, Beesley PW, Gundelfinger ED, Montag D (2014) Structure of excitatory synapses and GABAA receptor localization at inhibitory synapses are regulated by neuroplastin-65. J Biol Chem 289:8973-88
23. Beesley PW, Herrera-Molina R, Smalla KH, Seidenbecher CI (2014) The neuroplastin adhesion molecules: key regulators of neuronal plasticity and synaptic function. J Neurochem 131(3):268-83
24. Herrera-Molina R, Valdivia A, Kong M, Alvarez A, Cárdenas A, Quest AF, Leyton L (2013) Thy-1-interacting molecules and cellular signaling in cis and trans. Int Rev Cell Mol Biol 305:163-216
25. Kong M, Muñoz N, Valdivia A, Alvarez A, Herrera-Molina R, Cárdenas A, Schneider P, Burridge K, Quest AF, Leyton L (2013) Thy-1-mediated cell-cell contact induces astrocyte migration through the engagement of αVβ3 integrin and syndecan-4. BBA-Mol Cell Research 1833:1409-20
26. Sandoval M, Luarte A, Herrera-Molina R, Varas-Godoy M, Santibánez M, Rubio FJ, Smit AB, Gundelfinger ED, Li KW, Smalla KH, Wyneken U (2013) The glycolytic enzyme aldolase C is up-regulated in rat forebrain microsomes and in the cerebrospinal fluid after repetitive fluoxetine treatment. Brain Res 1520:1-14
27. Sarto-Jackson I, Milenkovic I, Smalla KH, Gundelfinger ED, Kaehne T, Herrera-Molina R, Thomas S, Kiebler MA, Sieghart W (2012) The cell adhesion molecule neuroplastin-65 is a novel interaction partner of γ-aminobutyric acid type A receptors. J Biol Chem 287:14201-14
28. Herrera-Molina R, Frischknecht R, Maldonado H, Seidenbecher CI, Gundelfinger ED, Hetz C, Aylwin Mde L, Schneider P, Quest AF, Leyton L (2012) Astrocytic αVβ3 integrin inhibits neurite outgrowth and promotes retraction of neuronal processes by clustering Thy-1. PLoS One 7(3):e34295.doi:10.1371/ journal.pone. 0034295
29. Herrera-Molina R, Flores B, Orellana JA, von Bernhardi R (2012) Modulation of interferon-γ-induced glial activation by transforming growth factor β1: a role for STAT1 and MAPK pathways. J Neurochem 123:113-23
30. Henríquez M, Herrera-Molina R, Valdivia A, Alvarez A, Kong M, Muñoz N, Eisner V, Jaimovich E, Schneider P, Quest AF, Leyton L (2011) ATP release due to Thy-1-integrin binding induces P2X7-mediated calcium entry required for focal adhesion formation. J Cell Sci 124:1581-8
31. Avalos AM, Valdivia AD, Muñoz N, Herrera-Molina R, Tapia JC, Lavandero S, Chiong M, Burridge K, Schneider P, Quest AF, Leyton L (2009) Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with alphavbeta3 integrin that activates PKCalpha and RhoA. J Cell Sci 122:3462-71
32. Uribe-San Martín R*, Herrera-Molina R*, Olavarría L, Ramírez G, von Bernhardi R (2008) Reduction of beta-amyloid-induced neurotoxicity on hippocampal cell cultures by moderate acidosis is mediated by transforming growth factor beta. Neuroscience 158(4):1338-47 (*co-first authorship)
33. Hermosilla T, Muñoz D, Herrera-Molina R, Valdivia A, Muñoz N, Nham SU, Schneider P, Burridge K, Quest AF, Leyton L (2008) Direct Thy-1/alphaVbeta3 integrin interaction mediates neuron to astrocyte communication. BBA-Mol Cell Research 1783:1111-20
34. Saud K*, Herrera-Molina R*, Von Bernhardi R (2005) Pro- and anti-inflammatory cytokines regulate the ERK pathway: implication of the timing for the activation of microglial cells. Neurotoxicity Research 8:277-87 (*co-first authorship)
35. Herrera-Molina R, von Bernhardi R (2005) Transforming growth factor-beta 1 produced by hippocampal cells modulates microglial reactivity in culture. Neurobiol Dis 19:229-36
1. Luarte A, Gallardo J, Corvalán D, Chakraborty A, Gouveia-Roque C, Bertin F, Contreras C, Ramírez JP, Weber A, Acevedo W, Zuschratter W, Herrera-Molina R, Wyneken U, Paula-Lima A, Adasme-Rocha T, Figueroa A, González C, González-Billault C, Hengst U, and Couve A. Local Synthesis of Reticulon-1C Lessens the Outgrowth of Injured Axons by Controlling Spastin Activity. [accessed Oct 13 2024]. Https://doi.org/10.1101/2024.08.11.607514
2. Xia, Z.; Arias-Gil, G.; Deckert, M.; Vollmer, M.; Curran, A.; Herrera-Molina, R.; Brosch, M.; Krug, K.; Schmidt, B.; Ohl, F. W.; Lippert, M. T.; Takagaki, K. Electrochemical Roughening and Carbon Nanotube Coating of Tetrodes for Chronic Single-Unit Recording. bioRxiv. bioRxiv August 21, 2019, p 738245. [link]
3. Vemula, S. K.; Malci, A.; Junge, L.; Lehmann, A.; Rama, R.; Hradsky, J.; Matute, R. A.; Weber, A.; Prigge, M.; Naumann, M.; Kreutz, M. R.; Seidenbecher, C. I.; Gundelfinger, E. D.; Herrera-Molina, R.. TRAF6 controls spinogenesis instructing synapse density and neuronal activity through binding neuroplastin. bioRxiv. bioRxiv September 14, 2019, p 768341. [link]
2025
Senior Investigator Symposium Award by the International Society for Neurochemistry. New York, The United State of America.
2020
Junkers Award for most innovative approaches in basic research. “Die Magdeburger Elektroden zur Aufzeichnung von Hirnaktivitäten und zur Behandlung von Hirnerkrankungen”. Alemania.
2019
Young Investigator Colloquia Award by the International Society for Neurochemistry. Montreal, Canada.
2016
Junkers Award for most innovative approaches in basic research. “Tiermodell Neuroplastinmutante zur Gedächtnisforschung”. Alemania.
2011
1. Visit by the Applicant to Another Laboratory. Committee for Aid and Education in Neurochemistry, United Kingdom.
2. Journal of Cell Science Travelling Fellowship. Editors of Journal of Cell Science and The Company of Biologists Limited. United Kingdom.
2010
Medal of Honour University of Chile for Excellence in Ph.D. Work. Chile.
2009
Estadía de Investigación en el Extranjero (DAAD n°A/09/73109). Alemania.
2008
1. Apoyo a la Realización de Tesis Doctoral (Conicyt n°24080153).
2. Eventos académicos y cursos cortos en el extranjero (Conicyt n°23090074).
3. Estadías Cortas de Investigación de la Vicerectoria de asuntos académicos de la Universidad de Chile. Chile.
2006
Realización de Doctorado (Conicyt n°21060447). Chile.
2005
Beca Instituto Ciencias Biomédicas (ICBM), Facultad de Medicina de la Universidad de Chile. Chile.
